One of the most studied probiotics in the world

BioGaia’s probiotic products with L. reuteri are among the most scientifically well-documented probiotics in the world with regard to both efficacy and safety. BioGaia’s different strains of L. reuteri have been studied in 258 clinical studies involving over 21,000 people of all ages (Dec 2022). Studies have been performed on the following:

  • Infantile colic and digestive health in children
  • Antibiotic-associated diarrhoea (AAD)
  • Acute diarrhoea
  • Gingivitis and inflammation of the gum
  • Periodontal disease
  • General health
  • Respiratory infections
  • Helicobacter pylori (the gastric ulcer bacterium)
  • Osteopenia

There have been 127 clinical studies involving L. reuteri in children, up to the age of 18 years old, and 131 studies involving adults, using BioGaia’s probiotic strains L. reuteri DSM 17938, L. reuteri ATCC PTA 6475 and L. reuteri ATCC PTA 5289.

Clinical studies


Research on bacteria

In the past decade, research on bacteria and their significance to our health has boomed, becoming one of the hottest research areas. At BioGaia, we have been researching Limosilactobacillus reuteri (formerly Lactobacillus reuteri) for more than 30 years.

A unique network of specialists at approximately 50 research institutes and clinics study not only the effectiveness of L. reuteri for various indications but also how and why it works.
Read more about our Research network

The importance of gut bacteria


Clinical trials supporting the use of BioGaia Probiotics ​

L. reuteri Protectis, Prodentis, and Gastrus

Clinical trials with BioGaias patented strains of L. reuteri

Our health areas

As an originator and world leader in probiotic dietary supplements, we offer products focused on gut health, mother & child health, bone health, oral health, and infection protection. Read more

Clinical studies

To date, 258 clinical studies using BioGaia’s human strains of L. reuteri have been performed on approximately 21,000 individuals of all ages. Results have been published in more than 200 articles in scientific journals (Dec 2022). Read more

What is L. reuteri?

Research has shown that L. reuteri is a species of bacteria that has developed a mutualistic relationship with its specific host over millions of years. Read more